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MEAT

This is the released version of MEAT; for the devel version, see MEAT.

Muscle Epigenetic Age Test


Bioconductor version: Release (3.20)

This package estimates epigenetic age in skeletal muscle, using DNA methylation data generated with the Illumina Infinium technology (HM27, HM450 and HMEPIC).

Author: Sarah Voisin [aut, cre] , Steve Horvath [ctb]

Maintainer: Sarah Voisin <sarah.voisin.aeris at gmail.com>

Citation (from within R, enter citation("MEAT")):

Voisin S, Harvey NR, Haupt LM, Griffiths LR, Ashton KJ, Coffey VG, Doering TM, Thompson JM, Benedict C, Cedernaes J, Lindholm ME, Craig JM, Rowlands DS, Sharples AP, Horvath S, Eynon N (2020). “An epigenetic clock for human skeletal muscle.” Journal of cachexia, sarcopenia and muscle, 11, 887.

Voisin S, Jacques M, Landen S, Harvey NR, Haupt LM, Griffiths LR, Gancheva S, Ouni M, Jähnert M, Ashton KJ, Coffey VG, Doering TM, Thompson JM, Gabory A, Junien C, Caiazzo R, Verkindt H, Raverdy V, Pattou F, Froguel P, Craig JM, Blocquiaux S, Thomis M, Sharples AP, Schürmann A, Roden M, Horvath S, Eynon N (2020). “Meta-analysis of genome-wide DNA methylation and integrative OMICs of age in human skeletal muscle.” BioRxiv.

Installation

To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MEAT")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MEAT")
MEAT HTML R Script
Reference Manual PDF
LICENSE Text

Details

biocViews BiomedicalInformatics, DNAMethylation, Epigenetics, MethylationArray, Microarray, Normalization, Preprocessing, Software
Version 1.18.0
In Bioconductor since BioC 3.11 (R-4.0) (5 years)
License MIT + file LICENSE
Depends R (>= 4.0)
Imports impute(>= 1.58), dynamicTreeCut (>= 1.63), glmnet (>= 2.0), grDevices, graphics, stats, utils, stringr, tibble, RPMM (>= 1.25), minfi(>= 1.30), dplyr, SummarizedExperiment, wateRmelon
System Requirements
URL https://github.com/sarah-voisin/MEAT
Bug Reports https://github.com/sarah-voisin/MEAT/issues
See More
Suggests knitr, markdown, rmarkdown, BiocStyle, testthat (>= 2.1.0)
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MEAT_1.18.0.tar.gz
Windows Binary (x86_64) MEAT_1.18.0.zip
macOS Binary (x86_64) MEAT_1.18.0.tgz
macOS Binary (arm64) MEAT_1.18.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/MEAT
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/MEAT
Bioc Package Browser https://code.bioconductor.org/browse/MEAT/
Package Short Url https://bioconductor.org/packages/MEAT/
Package Downloads Report Download Stats