This package is for version 3.9 of Bioconductor; for the stable, up-to-date release version, see SCAN.UPC.
Bioconductor version: 3.9
SCAN is a microarray normalization method to facilitate personalized-medicine workflows. Rather than processing microarray samples as groups, which can introduce biases and present logistical challenges, SCAN normalizes each sample individually by modeling and removing probe- and array-specific background noise using only data from within each array. SCAN can be applied to one-channel (e.g., Affymetrix) or two-channel (e.g., Agilent) microarrays. The Universal exPression Codes (UPC) method is an extension of SCAN that estimates whether a given gene/transcript is active above background levels in a given sample. The UPC method can be applied to one-channel or two-channel microarrays as well as to RNA-Seq read counts. Because UPC values are represented on the same scale and have an identical interpretation for each platform, they can be used for cross-platform data integration.
Author: Stephen R. Piccolo and Andrea H. Bild and W. Evan Johnson
Maintainer: Stephen R. Piccolo <stephen_piccolo at byu.edu>
Citation (from within R,
enter citation("SCAN.UPC")
):
To install this package, start R (version "3.6") and enter:
if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("SCAN.UPC")
For older versions of R, please refer to the appropriate Bioconductor release.
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("SCAN.UPC")
R Script | Primer | |
Reference Manual | ||
Text | NEWS |
biocViews | ImmunoOncology, Microarray, OneChannel, Preprocessing, RNASeq, Software, TwoChannel |
Version | 2.26.0 |
In Bioconductor since | BioC 2.11 (R-2.15) (7 years) |
License | MIT |
Depends | R (>= 2.14.0), Biobase(>= 2.6.0), oligo, Biostrings, GEOquery, affy, affyio, foreach, sva |
Imports | utils, methods, MASS, tools, IRanges |
LinkingTo | |
Suggests | pd.hg.u95a |
SystemRequirements | |
Enhances | |
URL | http://bioconductor.org http://jlab.bu.edu/software/scan-upc |
Depends On Me | |
Imports Me | |
Suggests Me | |
Links To Me | |
Build Report |
Follow Installation instructions to use this package in your R session.
Source Package | SCAN.UPC_2.26.0.tar.gz |
Windows Binary | SCAN.UPC_2.26.0.zip |
Mac OS X 10.11 (El Capitan) | SCAN.UPC_2.26.0.tgz |
Source Repository | git clone https://git.bioconductor.org/packages/SCAN.UPC |
Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/SCAN.UPC |
Package Short Url | https://bioconductor.org/packages/SCAN.UPC/ |
Package Downloads Report | Download Stats |
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