DeMAND

Bioconductor version: Release (3.19)

DEMAND predicts Drug MoA by interrogating a cell context specific regulatory network with a small number (N >= 6) of compound-induced gene expression signatures, to elucidate specific proteins whose interactions in the network is dysregulated by the compound.

Author: Jung Hoon Woo <jw2853 at columbia.edu>, Yishai Shimoni <ys2559 at columbia.edu>

Maintainer: Jung Hoon Woo <jw2853 at columbia.edu>, Mariano Alvarez <reef103 at gmail.com>

Citation (from within R, enter citation("DeMAND")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DeMAND")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DeMAND")

Using DeMAND	PDF	R Script
Reference Manual	PDF
LICENSE	Text

Need some help? Ask on the Bioconductor Support site!

Details

biocViews	GeneExpression, Network, NetworkEnrichment, Software, StatisticalMethod, SystemsBiology
Version	1.34.0
In Bioconductor since	BioC 3.2 (R-3.2) (9 years)
License	file LICENSE
Depends	R (>= 2.14.0), KernSmooth, methods
Imports
System Requirements
URL

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Build Report	Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	DeMAND_1.34.0.tar.gz
Windows Binary (x86_64)	DeMAND_1.34.0.zip (64-bit only)
macOS Binary (x86_64)	DeMAND_1.34.0.tgz
macOS Binary (arm64)	DeMAND_1.34.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/DeMAND
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/DeMAND
Bioc Package Browser	https://code.bioconductor.org/browse/DeMAND/
Package Short Url	https://bioconductor.org/packages/DeMAND/
Package Downloads Report	Download Stats