Bioconductor version: Release (3.15)
DoRothEA is a gene regulatory network containing signed transcription factor (TF) - target gene interactions. DoRothEA regulons, the collection of a TF and its transcriptional targets, were curated and collected from different types of evidence for both human and mouse. A confidence level was assigned to each TF-target interaction based on the number of supporting evidence.
Author: Daniel Dimitrov [cre] , Christian H. Holland [aut] , Luz Garcia-Alonso [aut], Alberto Valdeolivas [ctb], Minoo Ashtiani [ctb], Attila Gabor [ctb]
Maintainer: Daniel Dimitrov <daniel.dimitrov at uni-heidelberg.de>
Citation (from within R,
enter citation("dorothea")
):
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if (!require("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("dorothea")
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HTML | R Script | DoRothEA regulons. |
Reference Manual | ||
Text | NEWS | |
Text | LICENSE |
biocViews | ExperimentData, Homo_sapiens_Data, Mus_musculus_Data |
Version | 1.8.0 |
License | GPL-3 + file LICENSE |
Depends | R (>= 4.0) |
Imports | dplyr, magrittr, bcellViper, viper |
LinkingTo | |
Suggests | Biobase, BiocStyle, knitr, pheatmap, pkgdown, rmarkdown, Seurat, SingleCellExperiment, SummarizedExperiment, testthat (>= 2.1.0), tibble, tidyr, utils |
SystemRequirements | |
Enhances | |
URL | https://saezlab.github.io/dorothea/ https://github.com/saezlab/dorothea |
BugReports | https://github.com/saezlab/dorothea/issues |
Depends On Me | |
Imports Me | cosmosR, easier |
Suggests Me | MethReg |
Links To Me | |
Build Report |
Follow Installation instructions to use this package in your R session.
Source Package | dorothea_1.8.0.tar.gz |
Windows Binary | |
macOS Binary (x86_64) | |
Source Repository | git clone https://git.bioconductor.org/packages/dorothea |
Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/dorothea |
Package Short Url | https://bioconductor.org/packages/dorothea/ |
Package Downloads Report | Download Stats |
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