RNAAgeCalc

DOI: 10.18129/B9.bioc.RNAAgeCalc    

A multi-tissue transcriptional age calculator

Bioconductor version: Release (3.15)

It has been shown that both DNA methylation and RNA transcription are linked to chronological age and age related diseases. Several estimators have been developed to predict human aging from DNA level and RNA level. Most of the human transcriptional age predictor are based on microarray data and limited to only a few tissues. To date, transcriptional studies on aging using RNASeq data from different human tissues is limited. The aim of this package is to provide a tool for across-tissue and tissue-specific transcriptional age calculation based on GTEx RNASeq data.

Author: Xu Ren [aut, cre], Pei Fen Kuan [aut]

Maintainer: Xu Ren <xuren2120 at gmail.com>

Installation

To install this package, start R (version "4.2") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("RNAAgeCalc")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("RNAAgeCalc")

 

HTML	R Script	RNAAgeCalc
PDF		Reference Manual
Text		NEWS

Details

biocViews	GeneExpression, RNASeq, Software
Version	1.8.0
In Bioconductor since	BioC 3.11 (R-4.0) (2.5 years)
License	GPL-2
Depends	R (>= 3.6)
Imports	ggplot2, recount, impute, AnnotationDbi, org.Hs.eg.db, stats, SummarizedExperiment, methods
LinkingTo
Suggests	knitr, rmarkdown, testthat
SystemRequirements
Enhances
URL	https://github.com/reese3928/RNAAgeCalc
BugReports	https://github.com/reese3928/RNAAgeCalc/issues
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	RNAAgeCalc_1.8.0.tar.gz
Windows Binary	RNAAgeCalc_1.8.0.zip (64-bit only)
macOS Binary (x86_64)	RNAAgeCalc_1.8.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/RNAAgeCalc
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/RNAAgeCalc
Package Short Url	https://bioconductor.org/packages/RNAAgeCalc/
Package Downloads Report	Download Stats