NBSplice

DOI: 10.18129/B9.bioc.NBSplice    

Negative Binomial Models to detect Differential Splicing

Bioconductor version: Release (3.15)

The package proposes a differential splicing evaluation method based on isoform quantification. It applies generalized linear models with negative binomial distribution to infer changes in isoform relative expression.

Author: Gabriela A. Merino and Elmer A. Fernandez

Maintainer: Gabriela Merino <merino.gabriela33 at gmail.com>

Installation

To install this package, start R (version "4.2") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("NBSplice")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("NBSplice")

 

HTML	R Script	NBSplice-vignette
PDF		Reference Manual
Text		NEWS

Details

biocViews	AlternativeSplicing, DifferentialExpression, DifferentialSplicing, ImmunoOncology, RNASeq, Regression, Software, StatisticalMethod
Version	1.14.0
In Bioconductor since	BioC 3.8 (R-3.5) (4 years)
License	GPL (>=2)
Depends	R (>= 3.5), methods
Imports	edgeR, stats, MASS, car, mppa, BiocParallel, ggplot2, reshape2
LinkingTo
Suggests	knitr, RUnit, BiocGenerics, BiocStyle, rmarkdown, markdown
SystemRequirements
Enhances
URL	http://www.bdmg.com.ar
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	NBSplice_1.14.0.tar.gz
Windows Binary	NBSplice_1.14.0.zip
macOS Binary (x86_64)	NBSplice_1.14.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/NBSplice
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/NBSplice
Package Short Url	https://bioconductor.org/packages/NBSplice/
Package Downloads Report	Download Stats