ModCon

DOI: 10.18129/B9.bioc.ModCon    

Modifying splice site usage by changing the mRNP code, while maintaining the genetic code

Bioconductor version: Release (3.15)

Collection of functions to calculate a nucleotide sequence surrounding for splice donors sites to either activate or repress donor usage. The proposed alternative nucleotide sequence encodes the same amino acid and could be applied e.g. in reporter systems to silence or activate cryptic splice donor sites.

Author: Johannes Ptok [aut, cre]

Maintainer: Johannes Ptok <Johannes.Ptok at posteo.de>

Installation

To install this package, start R (version "4.2") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("ModCon")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("ModCon")

 

HTML	R Script	Designing SD context with ModCon
PDF		Reference Manual
Text		NEWS
Text		LICENSE

Details

biocViews	AlternativeSplicing, FunctionalGenomics, Software
Version	1.4.0
In Bioconductor since	BioC 3.13 (R-4.1) (1.5 years)
License	GPL-3 + file LICENSE
Depends	data.table, parallel, utils, stats, R (>= 4.1)
Imports
LinkingTo
Suggests	testthat, knitr, rmarkdown, dplyr, shinycssloaders, shiny, shinyFiles, shinydashboard, shinyjs
SystemRequirements	Perl
Enhances
URL	https://github.com/caggtaagtat/ModCon
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	ModCon_1.4.0.tar.gz
Windows Binary	ModCon_1.4.0.zip
macOS Binary (x86_64)	ModCon_1.4.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/ModCon
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/ModCon
Package Short Url	https://bioconductor.org/packages/ModCon/
Package Downloads Report	Download Stats