MOFA2

DOI: 10.18129/B9.bioc.MOFA2    

Multi-Omics Factor Analysis v2

Bioconductor version: Release (3.15)

The MOFA2 package contains a collection of tools for training and analysing multi-omic factor analysis (MOFA). MOFA is a probabilistic factor model that aims to identify principal axes of variation from data sets that can comprise multiple omic layers and/or groups of samples. Additional time or space information on the samples can be incorporated using the MEFISTO framework, which is part of MOFA2. Downstream analysis functions to inspect molecular features underlying each factor, vizualisation, imputation etc are available.

Author: Ricard Argelaguet [aut] , Damien Arnol [aut] , Danila Bredikhin [aut] , Britta Velten [aut, cre]

Maintainer: Britta Velten <britta.velten at gmail.com>

Installation

To install this package, start R (version "4.2") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MOFA2")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MOFA2")

 

HTML	R Script	Downstream analysis: Overview
HTML	R Script	MEFISTO on simulated data (temporal)
HTML	R Script	MOFA2: How to train a model in R
PDF		Reference Manual
Text		NEWS
Text		LICENSE

Details

biocViews	Bayesian, DimensionReduction, Software, Visualization
Version	1.6.0
In Bioconductor since	BioC 3.12 (R-4.0) (2 years)
License	GPL (>= 2) + file LICENSE
Depends	R (>= 4.0)
Imports	rhdf5, dplyr, tidyr, reshape2, pheatmap, ggplot2, methods, RColorBrewer, cowplot, ggrepel, reticulate, HDF5Array, grDevices, stats, magrittr, forcats, utils, corrplot, DelayedArray, Rtsne, uwot, basilisk, stringi
LinkingTo
Suggests	knitr, testthat, Seurat, ggpubr, foreach, psych, MultiAssayExperiment, SummarizedExperiment, SingleCellExperiment, ggrastr, mvtnorm, GGally, rmarkdown, data.table, tidyverse, BiocStyle, Matrix, markdown
SystemRequirements	Python (>=3), numpy, pandas, h5py, scipy, argparse, sklearn, mofapy2
Enhances
URL	https://biofam.github.io/MOFA2/index.html
BugReports	https://github.com/bioFAM/MOFA2
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	MOFA2_1.6.0.tar.gz
Windows Binary	MOFA2_1.6.0.zip
macOS Binary (x86_64)	MOFA2_1.6.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/MOFA2
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/MOFA2
Package Short Url	https://bioconductor.org/packages/MOFA2/
Package Downloads Report	Download Stats