drugTargetInteractions

DOI: 10.18129/B9.bioc.drugTargetInteractions    

Drug-Target Interactions

Bioconductor version: Release (3.14)

Provides utilities for identifying drug-target interactions for sets of small molecule or gene/protein identifiers. The required drug-target interaction information is obained from a local SQLite instance of the ChEMBL database. ChEMBL has been chosen for this purpose, because it provides one of the most comprehensive and best annotatated knowledge resources for drug-target information available in the public domain.

Author: Thomas Girke [cre, aut]

Maintainer: Thomas Girke <thomas.girke at ucr.edu>

Installation

To install this package, start R (version "4.1") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("drugTargetInteractions")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("drugTargetInteractions")

 

HTML	R Script	Drug-Target Interactions
PDF		Reference Manual
Text		NEWS

Details

biocViews	BiomedicalInformatics, Cheminformatics, Metabolomics, Pharmacogenetics, Pharmacogenomics, Proteomics, Software
Version	1.2.0
In Bioconductor since	BioC 3.13 (R-4.1) (1 year)
License	Artistic-2.0
Depends	methods, R (>= 4.1)
Imports	utils, RSQLite, UniProt.ws, biomaRt, ensembldb, BiocFileCache, dplyr, rappdirs, AnnotationFilter, S4Vectors
LinkingTo
Suggests	RUnit, BiocStyle, knitr, rmarkdown, ggplot2, reshape2, DT, EnsDb.Hsapiens.v86
SystemRequirements
Enhances
URL	https://github.com/girke-lab/drugTargetInteractions
BugReports	https://github.com/girke-lab/drugTargetInteractions
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	drugTargetInteractions_1.2.0.tar.gz
Windows Binary
macOS 10.13 (High Sierra)	drugTargetInteractions_1.2.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/drugTargetInteractions
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/drugTargetInteractions
Package Short Url	https://bioconductor.org/packages/drugTargetInteractions/
Package Downloads Report	Download Stats
Old Source Packages for BioC 3.14	Source Archive