celda

DOI: 10.18129/B9.bioc.celda    

CEllular Latent Dirichlet Allocation

Bioconductor version: Release (3.14)

Celda is a suite of Bayesian hierarchical models for clustering single-cell RNA-sequencing (scRNA-seq) data. It is able to perform "bi-clustering" and simultaneously cluster genes into gene modules and cells into cell subpopulations. It also contains DecontX, a novel Bayesian method to computationally estimate and remove RNA contamination in individual cells without empty droplet information. A variety of scRNA-seq data visualization functions is also included.

Author: Joshua Campbell [aut, cre], Shiyi Yang [aut], Zhe Wang [aut], Sean Corbett [aut], Yusuke Koga [aut]

Maintainer: Joshua Campbell <camp at bu.edu>

Installation

To install this package, start R (version "4.1") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("celda")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("celda")

 

HTML	R Script	Analysis of single-cell genomic data with celda
HTML	R Script	Estimate and remove cross-contamination from ambient RNA in single-cell data with DecontX
PDF		Reference Manual
Text		NEWS
Text		LICENSE

Details

biocViews	Bayesian, Clustering, GeneExpression, Sequencing, SingleCell, Software
Version	1.10.0
In Bioconductor since	BioC 3.9 (R-3.6) (3 years)
License	MIT + file LICENSE
Depends	R (>= 4.0)
Imports	plyr, foreach, ggplot2, RColorBrewer, grid, scales, gtable, grDevices, graphics, matrixStats, doParallel, digest, methods, reshape2, S4Vectors, data.table, Rcpp, RcppEigen, uwot, enrichR, SummarizedExperiment, MCMCprecision, ggrepel, Rtsne, withr, scater(>= 1.14.4), scran, SingleCellExperiment, dbscan, DelayedArray, stringr, Matrix, ComplexHeatmap, multipanelfigure, circlize
LinkingTo	Rcpp, RcppEigen
Suggests	testthat, knitr, roxygen2, rmarkdown, biomaRt, covr, BiocManager, BiocStyle, TENxPBMCData, singleCellTK, M3DExampleData
SystemRequirements
Enhances
URL
BugReports	https://github.com/campbio/celda/issues
Depends On Me
Imports Me	singleCellTK
Suggests Me
Links To Me
Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	celda_1.10.0.tar.gz
Windows Binary	celda_1.10.0.zip (32- & 64-bit)
macOS 10.13 (High Sierra)	celda_1.10.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/celda
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/celda
Package Short Url	https://bioconductor.org/packages/celda/
Package Downloads Report	Download Stats
Old Source Packages for BioC 3.14	Source Archive