DominoEffect

DOI: 10.18129/B9.bioc.DominoEffect    

Identification and Annotation of Protein Hotspot Residues

Bioconductor version: Release (3.14)

The functions support identification and annotation of hotspot residues in proteins. These are individual amino acids that accumulate mutations at a much higher rate than their surrounding regions.

Author: Marija Buljan and Peter Blattmann

Maintainer: Marija Buljan <marija.buljan.2 at gmail.com>, Peter Blattmann <blattmann at imsb.biol.ethz.ch>

Installation

To install this package, start R (version "4.1") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DominoEffect")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DominoEffect")

 

HTML	R Script	Vignette for DominoEffect package
PDF		Reference Manual
Text		NEWS

Details

biocViews	Alignment, Proteomics, SequenceMatching, Software, SomaticMutation
Version	1.14.0
In Bioconductor since	BioC 3.7 (R-3.5) (4 years)
License	GPL (>= 3)
Depends	R (>= 3.5)
Imports	biomaRt, data.table, utils, stats, Biostrings, SummarizedExperiment, VariantAnnotation, AnnotationDbi, GenomeInfoDb, IRanges, GenomicRanges, methods
LinkingTo
Suggests	knitr, testthat, rmarkdown
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	DominoEffect_1.14.0.tar.gz
Windows Binary	DominoEffect_1.14.0.zip
macOS 10.13 (High Sierra)	DominoEffect_1.14.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/DominoEffect
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/DominoEffect
Package Short Url	https://bioconductor.org/packages/DominoEffect/
Package Downloads Report	Download Stats
Old Source Packages for BioC 3.14	Source Archive