msviperClass {viper} | R Documentation |
This function generates an instance of the msviper class from a signature, NES signature and regulon object
msviperClass(nes, signature, regulon, nullmodel = NULL)
nes |
Numeric vector of NES values |
signature |
Numeric vector of gene expression signature |
regulon |
Instance of class regulon |
nullmodel |
Optional matrix containing the signatures for the null model |
msviper class object
data(bcellViper, package="bcellViper") sig <- rowTtest(dset, "description", c("CB", "CC"), "N")$statistic mra <- msviper(sig, regulon) mra1 <- msviperClass(mra$es$nes, sig, regulon) summary(mra1) plot(mra1)