pam50 {genefu}R Documentation

PAM50 classifier for identification of breast cancer molecular subtypes (Parker et al 2009)

Description

List of parameters defining the PAM50 classifier for identification of breast cancer molecular subtypes (Parker et al 2009).

Usage

data(pam50)
data(pam50.scale)
data(pam50.robust)

Format

List of parameters for PAM50:

Details

Three versions of the model are provided, each of ones differs by the gene expressions standardization method since it has an important impact on the subtype classification:

Source

http://jco.ascopubs.org/cgi/content/short/JCO.2008.18.1370v1

References

Parker, Joel S. and Mullins, Michael and Cheang, Maggie C.U. and Leung, Samuel and Voduc, David and Vickery, Tammi and Davies, Sherri and Fauron, Christiane and He, Xiaping and Hu, Zhiyuan and Quackenbush, John F. and Stijleman, Inge J. and Palazzo, Juan and Marron, J.S. and Nobel, Andrew B. and Mardis, Elaine and Nielsen, Torsten O. and Ellis, Matthew J. and Perou, Charles M. and Bernard, Philip S. (2009) "Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes", Journal of Clinical Oncology, 27(8):1160–1167


[Package genefu version 2.26.0 Index]