.OriginalModel_NoRetraining {TBSignatureProfiler} | R Documentation |
A function to obtain predicted score for TB gene signatures that do not need to be retrained.
.OriginalModel_NoRetraining(input, useAssay, geneSignaturesName, BPPARAM)
input |
A SummarizedExperiment object with gene symbols as the assay row names. |
useAssay |
A character string or an integer specifying the assay in the
|
geneSignaturesName |
A character string/vector specifying the signature
of interest. If |
BPPARAM |
An instance inherited from |
Anderson_42 and Anderson_OD_51 used difference of sums to calculate prediction scores. Difference of sums is obtained by subtracting the sum of the expression of genes within signatures that are down-regulated from the sum of the expression of genes that are up-regulated within signatures. Kaforou_27, Kaforou_OD_44, and Kaforou_OD_53 used difference of arithmetic means to calculate prediction scores. Sweeney_OD_3 used difference of arithmetic mean to calculate prediction score.
A SummarizedExperiment object with predicted scores for each sample obtained from the signature's original model.