COVIDsignatures {TBSignatureProfiler}R Documentation

A list of published/pre-print COVID-19 signatures.

Description

A set of 47 COVID-19 gene signatures from various single-cell and bulk RNA-seq publications and preprint manuscripts from early- to mid-2020. This set of signatures uses gene symbols.

Usage

COVIDsignatures

Format

list

Details

Signature names are composed of the last name of the primary author, followed by the type of sequencing data from which the signature was derived, the tissue from which the signature was derived, and ending with a reference to the cell type, infection status, or disease to which the signature belongs, as defined in the original publication.

Note that in some cases signatures will be positive identifiers of COVID-19 as positive markers of immune cell clusters are often provided for single-cell RNA-seq data; this should be taken into account when creating ROC curves and computing any AUC or disease risk estimates.

Source

Examples

data("COVIDsignatures")

[Package TBSignatureProfiler version 1.6.0 Index]