SDAMS-package {SDAMS}R Documentation

SDAMS package for differential abundance/expression analysis of Metabolomics, Proteomics and single-cell RNA sequencing data

Description

SDAMS is an R package for differential abundance/expression analysis of metabolomics, proteomics and single-cell RNA sequencing data, and the main function for differential abundance/expression analysis is SDA. See the examples at SDA for basic analysis steps. SDAMS considers a two-part model, a logistic regression for the zero proportion and a semi-parametric log-linear model for the non-zero values.

Author(s)

Yuntong Li <yuntong.li@uky.edu>, Chi Wang <chi.wang@uky.edu>, Li Chen <lichenuky@uky.edu>

References

Li, Y., Fan, T.W., Lane, A.N. et al. SDA: a semi-parametric differential abundance analysis method for metabolomics and proteomics data. BMC Bioinformatics 20, 501 (2019).


[Package SDAMS version 1.14.0 Index]