twoFounderSharingProb {RVS}R Documentation

sharing probability when founder pair introduces variant

Description

In the case of relatedness among founders, assume that up to two founders could introduce the variant and condition on all possible pairs.

Usage

twoFounderSharingProb(procPed, kinshipCoeff, kinshipOrder)

Arguments

procPed

pedigree that has been through processPedigree()

kinshipCoeff

mean kinship coefficient among the founders

kinshipOrder

order of the polynomial approximation to the distribtion of the number of distinct alleles in the founders (d in Bureau et al.). Must be <= 5

Value

sharing probability


[Package RVS version 1.16.0 Index]