sigInteractorsDIGGIT {MOMA}R Documentation

Filter interactions from NES (DIGGIT) scores and corresponding background-corrected scores.

Description

Use this version in the Bayes model to rank TFs

Usage

sigInteractorsDIGGIT(
  corrected.scores,
  nes.scores,
  cindy,
  p.thresh = 0.05,
  cindy.only = TRUE
)

Arguments

corrected.scores

A list indexed by the genomic event/gene with corresponding pvals and qvals for each TF

nes.scores

Matrix with tfs as columns, rows are genomic events

cindy

CINDy algorithm output matrix

p.thresh

P-value threshold (default=0.05)

cindy.only

Consider only CINDy validated interactions (default=TRUE)

Value

a list (indexed by VIPER protein) of significant genomic interactions and associated pvals over the background (null TF) model, and NES scores


[Package MOMA version 1.6.0 Index]