get_prior_Gerstein {KBoost} | R Documentation |
Function to build a prior using a previously built Network on ChIP-Seq.
get_prior_Gerstein(gen_names, TFs, pos_weight, neg_weight)
gen_names |
the gene names in Symbol nomenclature. |
TFs |
the indexes of gene names which are TFs. |
pos_weight |
the prior weight for edges previously found in Gerstein 2011 |
neg_weight |
the prior weight for edges not found in the Gerstein 2011/ |
matrix with prior probabilities of the Tf target edges.
gen_names = c("TP53","MDM2","FOXM1","ESR1","CTCF","YY1") tfs = get_tfs_human(gen_names) prior = get_prior_Gerstein(gen_names,tfs,0.6,0.4)