remove_homologous_interactions {STRINGdb} | R Documentation |
With this method it is possible to remove the interactions that are composed by a pair of homologous/similar proteins, having a similarity bitscore between each other higher than a threshold.
## S4 method for signature 'STRINGdb' remove_homologous_interactions(interactions_dataframe, bitscore_threshold = 60)
interactions_dataframe |
a data frame contaning the sorted interactions to be benchmarked. The data frame should have the following column names: proteinA, proteinB, score |
bitscore_threshold |
filter out pairs of homologous proteins, having a similarity bitscore higher than this parameter |
interactions data frame where the homologous pairs have been removed, from the input interactions' data frame
Andrea Franceschini