path_genes_by_cell_type {KEGGlincs} | R Documentation |
Check quantity of data across cell lines available from LINCS corresponding to the pathway of interest
path_genes_by_cell_type(KEGG_mappings, pert_time = 96, get_KOs = FALSE, generate_plot = TRUE)
KEGG_mappings |
KEGG_mappings The data.frame object generated by the function expand_KEGG_mappings |
pert_time |
Choose from (6,24,48,96,120,144,168) |
get_KOs |
Logical indicator to have data frame returned |
generate_plot |
Logical indicator to generate histogram |
A plot depicting percentage of pathway genes knocked-out by cell line and a data frame object listing the genes [by cell line]
p53_KGML <- get_KGML("hsa04115") p53_KEGG_mappings <- expand_KEGG_mappings(p53_KGML) path_genes_by_cell_type(p53_KEGG_mappings)