detectionPoobEcdf2 {sesame}R Documentation

Detection P-value based on ECDF of out-of-band signal

Description

aka pOOBAH2 (p-vals by Out-Of-Band Array Hybridization)

Usage

detectionPoobEcdf2(sset, force = FALSE)

pOOBAH2(sset, force = FALSE)

Arguments

sset

a SigSet

force

force rerun even if result already exists

Details

The function takes a SigSet as input, computes detection p-value using out-of-band probes empirical distribution and returns a new SigSet with an updated pval slot.

The difference between this function and the original pOOBAH is that pOOBAH2 is based on background-subtracted and dyebias corrected signal and do not distinguish the color channel difference.

Value

detection p-value

Examples

sset <- makeExampleSeSAMeDataSet()
sset <- detectionPoobEcdf(sset)

sset <- makeExampleSeSAMeDataSet()
sset <- pOOBAH2(sset)

[Package sesame version 1.8.10 Index]