detectionPnegNormTotal {sesame}R Documentation

Detection P-value based on normal fitting the negative controls, channels are first summed

Description

The function takes a SigSet as input, computes detection p-value using negative control probes parametrized in a normal distribution with the two channels summed first and returns a new SigSet with an updated pval slot. The SD is summed to emulate the SD of the summed signal (not the most accurate treatment).

Usage

detectionPnegNormTotal(sset, force = FALSE)

Arguments

sset

a SigSet

force

force rerun even if result already exists

Value

detection p-value

Examples

sset <- makeExampleSeSAMeDataSet()
sset <- detectionPnegNormTotal(sset)


[Package sesame version 1.8.10 Index]