noobsb {sesame}R Documentation

Background subtraction with bleeding-through subtraction

Description

The function takes a SigSet and returns a modified SigSet with background subtracted. Signal bleed-through was modelled using a linear model with error estimated from cross-channel regression. Norm-Exp deconvolution using Out-Of-Band (oob) probes.

Usage

noobsb(sset, offset = 15, detailed = FALSE)

Arguments

sset

a SigSet

offset

offset

detailed

if TRUE, return a list of SigSet and regression function

Value

a modified SigSet with background correction

Examples

sset <- makeExampleSeSAMeDataSet('HM450')
sset.nb <- noobsb(sset)

[Package sesame version 1.8.10 Index]