ct.RRAalpha {gCrisprTools} | R Documentation |
This function is called internally as a single instance of the beta aggregation step in RRAa. Users should not interact with it directly.
The expected input is a list of rank statistics, and a paired alpha
argument defining which values to consider in downstream analyses (see below).
ct.RRAalpha(p, g.key, shuffle = FALSE)
p |
A single column matrix of rank statistics, with |
g.key |
data.frame with guide and gene names |
shuffle |
Logical indicating whether to shuffle the rank statistics prior to calculating the rho statistics (useful for permutation). |
Nothing, or a named list of target-level P-values, which are treated as a rho statistic in the permutation step.
Russell Bainer
data('fit') data('ann') geneScores <- ct.RRAalpha(fit$p.value, ann, shuffle = FALSE)