estOff {combi} | R Documentation |
Estimate the row/column parameters of the independence model
estOff(data, distribution, rowOff, colOff, meanVarTrend, col, newtonRaphson, libSizes, ...)
data |
a list of data matrices with the same number of samples n in the rows. Also phyloseq objects are acceptable |
distribution |
a character string describing which distributional assumption should be used. |
rowOff, colOff |
current row and column offset estimates |
meanVarTrend |
The estimated mean-variance trend |
col |
A logical, should column offsets be estimated |
newtonRaphson |
A boolean, should Newton-Raphson be used to solve the estimating equations |
libSizes |
The library sizes, used to evaluate the mean-variance trend |
... |
passed onto nleqslv |
The estimated marginal parameters