PTMnormalize {MSstatsPTM} | R Documentation |
PTMnormalize
normalizes log2-intensities of spectral features across
MS runs using a reference, or by equalizing a chosen summary (the log2
intensity summation, median, or mean of log2-intensities) from all features,
features of modified peptides or features of unmodified peptides.
PTMnormalize(data, method = "median", refs)
data |
A list of two data frames named |
method |
A string defining the normalization method. Default is
|
refs |
A list of two data frames named |
Normalized data stored as in data
.
sim <- PTMsimulateExperiment( nGroup=2, nRep=2, nProtein=1, nSite=1, nFeature=5, logAbundance=list( PTM=list(mu=25, delta=c(0, 1), sRep=0.2, sPeak=0.05), PROTEIN=list(mu=25, delta=c(0, 1), sRep=0.2, sPeak=0.05) ) ) PTMnormalize(sim)