setDepthFactors {MPRAnalyze} | R Documentation |
Manually set library depth correction factors
setDepthFactors(obj, dnaDepth, rnaDepth)
obj |
the MpraObject |
dnaDepth |
library size factors for the DNA data, a numeric vector of length of the number of columns in the DNA data matrix |
rnaDepth |
library size factors for the RNA data, a numeric vector of length of the number of columns in the RNA data matrix |
the MpraObject with library depth factors
data <- simulateMPRA(tr = rep(2,10), da=NULL, nbatch=2, nbc=20) obj <- MpraObject(dnaCounts = data$obs.dna, rnaCounts = data$obs.rna, colAnnot = data$annot) ## set constant depth factors (no depth correction) obj <- setDepthFactors(obj, dnaDepth = rep(1, NCOL(data$obs.dna)), rnaDepth = rep(1, NCOL(data$obs.rna)))