synergyfinder

DOI: 10.18129/B9.bioc.synergyfinder    

Calculate and Visualize Synergy Scores for Drug Combinations

Bioconductor version: Release (3.11)

Efficient implementations for all the popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of the synergy scores as either a two-dimensional or a three-dimensional interaction surface over the dose matrix.

Author: Liye He <liye.he at helsinki.fi>, Jing Tang <jing.tang at helsinki.fi>, Shuyu Zheng <shuyu.zheng at helsinki.fi>

Maintainer: Shuyu Zheng <shuyu.zheng at helsinki.fi>

Installation

To install this package, start R (version "4.0") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("synergyfinder")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("synergyfinder")

 

PDF	R Script	synergyfinder
PDF		Reference Manual
Text		NEWS

Details

biocViews	Software, StatisticalMethod
Version	2.2.4
In Bioconductor since	BioC 3.4 (R-3.3) (4 years)
License	Mozilla Public License 2.0
Depends	R (>= 3.6.0), methods
Imports	drc (>= 2.5-12), reshape2 (>= 1.4.1), ggplot2 (>= 2.1.0), grid (>= 3.2.4), lattice (>= 0.20-33), nleqslv (>= 3.0), stats (>= 3.3.0), graphics (>= 3.3.0), grDevices (>= 3.3.0)
LinkingTo
Suggests	knitr, rmarkdown
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	synergyfinder_2.2.4.tar.gz
Windows Binary	synergyfinder_2.2.4.zip (32- & 64-bit)
macOS 10.13 (High Sierra)	synergyfinder_2.2.4.tgz
Source Repository	git clone https://git.bioconductor.org/packages/synergyfinder
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/synergyfinder
Package Short Url	https://bioconductor.org/packages/synergyfinder/
Package Downloads Report	Download Stats
Old Source Packages for BioC 3.11	Source Archive