readXCI {XCIR}R Documentation

Read a list of known inactivated genes

Description

Read a list of gene symbols of known inactivated genes to be used as training set in betaBinomXI.

Usage

readXCI(xciGenes = NULL)

Arguments

xciGenes

A character or codeNULL. By defaults, return a vector of 177 genes. Other available choices include "cotton" and "intersect". If a file path is given, the genes will be read from the file.

Details

Both gene lists are extracted from Cotton et al. Genome Biology (2013). doi:10.1186/gb-2013-14-11-r122. By default, the function returns a list that was used as training set in the paper. This training set was generated as the intersection of the silenced genes identified by both expression (Carrel & Willard, 2005) and DNA methylation analysis (Cotton et al, 2011). Setting it to "cotton" will instead return a list of 294 genes that were classified as inactivated by Cotton et al. "intersect" is the most stringent list which returns the intersection of training and predicted set.

Value

A character vector of gene names.

See Also

betaBinomXI

Examples

xcig <- readXCI()
xcig <- readXCI("cotton")


[Package XCIR version 1.0.0 Index]