P.preestimation {NTW} | R Documentation |
Pre-estimate the potential transcriptional perturbation targets matrix P according to gene expression data X . Those genes with the changes in top topK will be assumed as possible targets of the perturbations.
P.preestimation(X, topK)
X |
Gene expression data, a matrix with rows as genes and columns as experiments. |
topK |
The number of possible targets of the perturbations. |
A matrix with the same structure of X or P.
Wei Xiao, Yin Jin, Darong Lai, Xinyi Yang, Yuanhua Liu, Christine Nardini
data(sos.data) X<-sos.data X<-as.matrix(X) IX<-P.preestimation(X, topK= round(0.6*nrow(X))) IX