fixMVs {MmPalateMiRNA} | R Documentation |
RGList
object with missing values.
Imputes missing values in one of the red foreground, red background,
green foreground, or green background matrices of an RGList
object created from Miltenyi Biotech miRXplore Microarrays.
Uses the replicate structure of the array to impute the missing
values. Implicit assumption is that only
one of the four replicated values for a probe is an missing value.
fixMVs(mat, idx, gene.ids)
mat |
One of the red foreground ( |
idx |
Index of missing values, as returned by the
|
gene.ids |
Vector of gene IDs for each probe. See examples for usage. |
The function is specific to RGList
objects which were created
from Miltenyi Biotech miRXplore Microarrays,
since it depends on the replicated
structure of that array (probes spotted in quadruplicate) to impute
the missing probe values.
Returns a matrix with the missing probe values imputed.
checkMVs
, checkOutliers
,
fixOutliers
data(PalateData) mvs <- checkMVs(PalateData) PalateData$Rb <- fixMVs(PalateData$Rb, mvs$Rb.na, PalateData$genes$Gene)