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source("https://bioconductor.org/biocLite.R")
biocLite("TargetScore")

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TargetScore

 

TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information

Bioconductor version: Release (3.1)

Infer the posterior distributions of microRNA targets by probabilistically modelling the likelihood microRNA-overexpression fold-changes and sequence-based scores. Variaitonal Bayesian Gaussian mixture model (VB-GMM) is applied to log fold-changes and sequence scores to obtain the posteriors of latent variable being the miRNA targets. The final targetScore is computed as the sigmoid-transformed fold-change weighted by the averaged posteriors of target components over all of the features.

Author: Yue Li

Maintainer: Yue Li <yueli at cs.toronto.edu>

Citation (from within R, enter citation("TargetScore")):

Installation

To install this package, start R and enter:

## try http if https is not available
source("https://bioconductor.org/biocLite.R")
biocLite("TargetScore")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("TargetScore")

 

PDF R Script TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information
PDF   Reference Manual
Text   NEWS

Details

biocViews Software, miRNA
Version 1.6.0
In Bioconductor since BioC 2.13 (R-3.0) (2 years)
License GPL-2
Depends pracma, Matrix
Imports
LinkingTo
Suggests TargetScoreData, gplots, Biobase, GEOquery
SystemRequirements
Enhances
URL http://www.cs.utoronto.ca/~yueli/software.html
Depends On Me
Imports Me
Suggests Me TargetScoreData
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Package Source TargetScore_1.6.0.tar.gz
Windows Binary TargetScore_1.6.0.zip
Mac OS X 10.6 (Snow Leopard) TargetScore_1.6.0.tgz
Mac OS X 10.9 (Mavericks) TargetScore_1.6.0.tgz
Subversion source (username/password: readonly)
Git source https://github.com/Bioconductor-mirror/TargetScore/tree/release-3.1
Package Short Url http://bioconductor.org/packages/TargetScore/
Package Downloads Report Download Stats

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