To install this package, start R and enter:

## try http if https is not available
source("https://bioconductor.org/biocLite.R")
biocLite("FEM")

In most cases, you don't need to download the package archive at all.

FEM

 

Identification of Functional Epigenetic Modules

Bioconductor version: Release (3.1)

The FEM package performs a systems-level integrative analysis of DNA methylation and gene expression data. It seeks modules of functionally related genes which exhibit differential promoter DNA methylation and differential expression, where an inverse association between promoter DNA methylation and gene expression is assumed. For full details, see Jiao et al Bioinformatics 2014.

Author: Andrew E. Teschendorff and Yinming Jiao

Maintainer: Andrew E. Teschendorff <andrew at picb.ac.cn>

Citation (from within R, enter citation("FEM")):

Installation

To install this package, start R and enter:

## try http if https is not available
source("https://bioconductor.org/biocLite.R")
biocLite("FEM")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("FEM")

 

PDF R Script The FEM package performs a systems-level integrative analysis of DNA methylationa and gene expression. It seeks modules of functionally related genes which exhibit differential promoter DNA methylation and differential expression, where an inverse association between promoter DNA methylation and gene expression is assumed. For full details, see Jiao et al Bioinformatics 2014.
PDF   Reference Manual

Details

biocViews DifferentialExpression, DifferentialMethylation, NetworkEnrichment, Software, SystemsBiology
Version 2.2.1
In Bioconductor since BioC 3.0 (R-3.1) (1 year)
License GPL (>=2)
Depends AnnotationDbi, Matrix, marray, corrplot, igraph, impute, limma, org.Hs.eg.db
Imports graph
LinkingTo
Suggests
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Package Source FEM_2.2.1.tar.gz
Windows Binary FEM_2.2.1.zip
Mac OS X 10.6 (Snow Leopard) FEM_2.2.1.tgz
Mac OS X 10.9 (Mavericks) FEM_2.2.1.tgz
Subversion source (username/password: readonly)
Git source https://github.com/Bioconductor-mirror/FEM/tree/release-3.1
Package Short Url http://bioconductor.org/packages/FEM/
Package Downloads Report Download Stats

Documentation »

Bioconductor

R / CRAN packages and documentation

Support »

Please read the posting guide. Post questions about Bioconductor to one of the following locations:

Fred Hutchinson Cancer Research Center